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Struggling with Chronic Low Back Pain?

You may be eligible to join a clinical trial exploring a new plant-based investigational medication - trial-related care at no cost to you.

If you've been living with persisting low back pain for more than six months and haven’t found lasting relief, you may be eligible for a clinical trial exploring an investigational medication for Chronic Low Back Pain (CLBP).

What is This Clinical Trial About?

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Chronic low back pain is a common condition that affects millions worldwide and, for many, finding an effective treatment can be a long and challenging journey. This clinical trial is looking at the effects of a plant-based investigational medication in participants with chronic low back pain. 

 

Why Participate?

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• No Cost for Trial-Related Care
You will not be charged for trial-related exams, procedures, and medications.

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• Compensation for Your Time and Effort
You will be reimbursed for your time and travel expenses.

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• Contribute to the Future of Pain Relief
Your participation may help researchers better understand chronic low back pain and inform future treatment options.

 

Are There Any Risks?

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While the trial team prioritizes your safety, participating in a clinical trial does carry potential risks. These may include side effects from the investigational medication, such as dizziness or irregular heartbeat, and minor discomfort from trial procedures, such as blood draws. Before enrolling, you’ll receive full information about all potential risks and have the opportunity to ask questions.

 

Who Can Join?

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You may be eligible if you:

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• are a U.S. resident

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• are 18 years or older

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• have experienced chronic low back pain for more than six months

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• have not found relief with standard pain medication

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• are not currently pregnant or breastfeeding

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• do not have severe physical or mental health conditions

 

What Does Participation Involve?

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• Trial Duration: 5-20 months (depending on the trial phases you want to participate in)

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• Visits: 8-23 trial visits, scheduled every 2-5 weeks

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• Treatment: You will receive either the investigational medication or a placebo

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• Care: All trial-related healthcare is provided at no cost

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• Compensation: You will be reimbursed for your time and travel expenses

 

Ready to Take the First Step?

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Fill out the form below.

A member of the trial team will contact you to discuss your eligibility and guide you through the next steps.

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I understand this is a research study prescreen (not medical care) and I agree to be contacted.
Yes
No
What is your age?
Under 18
18–39
40–64
65+
Have you tested positive for COVID‑19 within the past 4 days?
Yes
No
Do you have 2 or more COVID-19 Symptoms (Fever or chills, Cough,Shortness of breath or difficulty breathing,Sore throat, Congestion or runny nose,New loss of taste or smell,Fatigue (tiredness),Muscle or body aches,Headache,Nausea or vomiting,Diarrhea)
Yes
No

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I understand this is a research study prescreen (not medical care) and I agree to be contacted.

Want us to text you back? Enter your mobile number and (optional) consent to receive SMS about your inquiry and service notifications. Msg frequency varies. Msg & data rates may apply. Reply STOP to opt out. Privacy Policy | Terms

The below questions and selections are used to determine your eligibility in the study only:

DOB
Month
Day
Year
What is your current age?
Under Age 18
Age 18-35
Age 36- 54
Age 55+
Have you been diagnosed with Chronic Low Back Pain by a qualified physician?
Yes
No
Are you currently taking a medication(s) for chronic low back pain?
Yes
No
What is your gender?
Male
Female
What racial group do you identify with?
Black or African-American
Asian
White
Hispanic

What is your height and weight?

For how long have you been experiencing pain that starts in your lower back and radiates (shoots, travels) down into your leg(s) to below the knee?
6 months or longer
Shorter than 6 months
I don't know
Thinking about the past 6 months, on a scale from 0 to 10, where 0 means no pain and 10 means the worst pain imaginable, how severe has the pain been on average in your worst-affected leg?
0-4
5-9
10
Which statement best describes where you feel your pain? Select the one that fits best.
The pain is only in my lower back
The pain radiates from my lower back into my upper leg, but stops at or above the knee
The pain radiates from my lower back down to below the knee and is exactly the same in both legs
The pain radiates from my lower back down to below the knee in only one leg or, if in both legs, the pain is more severe in one of the legs
When do you feel leg pain?
The pain occurs only when I walk, and goes away completely when I rest
The pain is also present when I rest
Compared to your low back pain, how intense is your leg pain?
My leg pain is less intense than my low back pain
My leg pain is about the same as my low back pain
My leg pain is more intense than my low back pain 3

Has a doctor told you that your chronic low back pain including pain radiating into your leg(s) is caused by any of the following, or have you had any of the following?

▪ Infection or abscess in the spine

▪ Spinal fracture

▪ Tumor (cancer) affecting the spine or nerves

▪ Major back trauma or back surgery in the last 6 months

▪ Interventional pain procedures in your lower back in the last 3 months (e.g., epidural or depot steroid injection, nerve block, radiofrequency ablation)

▪ An implanted spinal cord stimulator, peripheral nerve stimulator, or intrathecal (pain) pump

(9) Select one of the options below:
Yes, one or more of the above
No, none of the above
Have you ever taken non-opioid pain medication for your chronic low back pain including pain radiating into your leg(s), and if so, did it help enough? Examples for non-opioid pain medication: Diclofenac, meloxicam, ibuprofen (Advil)
Yes, and it helped enough
Yes, but it did not help enough
I could not take it because of side effects or because my doctor told me not to
I have never taken non-opioid pain medication for my chronic low back pain including pain radiating into my leg(s)
Have you taken pain medication for your chronic low back pain including pain radiating into your leg(s) on at least 4 out of 7 days per week during the past 3 months?
Yes
No
In the last 8 weeks, have you received any non-drug treatment for your leg pain (such as physical therapy, behavioral therapy, acupuncture, massage, or mobilization) that clearly changed your pain?
Yes, and I am willing and able to keep it unchanged during the trial.
Yes, and I am not willing or able to keep it unchanged during the trial.
Yes, but the type, dose, or frequency was changed within the last 8 weeks
No
In the last 8 weeks, have you received any non-drug treatment for your leg pain (such as physical therapy, behavioral therapy, acupuncture, massage, or mobilization) that clearly changed your pain?
Yes, and I am willing and able to keep it unchanged during the trial.
Yes, and I am not willing or able to keep it unchanged during the trial.
Yes, but the type, dose, or frequency was changed within the last 8 weeks
No

Have you ever been diagnosed with any of the following conditions?

▪ Severe form of an autoimmune disease

▪ Crigler-Najjar syndrome or Rotor syndrome

▪ Severe blood (hematological) disease

▪ Severe hormone (endocrine) disease, including untreated clinical hypothyroidism

▪ Severe lung (respiratory) disease

▪ Severe heart disease, or a heart attack, heart failure, serious arrhythmia, poorly controlled high blood pressure, or long-QT syndrome within the last 12 months

▪ Severe disease of the nervous system or digestive system

▪ Severe liver disease

▪ Severe kidney disease

▪ Epilepsy or any type of seizure

▪ Severe traumatic brain injury

▪ HIV (human immunodeficiency virus)

▪ Schizophrenia, bipolar disorder, any psychotic disorder, post-traumatic stress disorder, severe anxiety or panic disorder

▪ Severe depression

▪ Suicidal ideation

(13) Select one of the options below:
Yes, one or more of the above
No, none of the above
Have you had cancer within the past 5 years? Do not select, yes, if you had Basal-cell or squamous-cell skin cancer that was fully removed and has not come back, or cervical cancer in situ fully removed with a negative pap test
Yes
No
Are you currently taking any antidepressant or anti-seizure/anticonvulsant medication? Examples: •Antidepressants: Amitriptyline, imipramine, mirtazapine, bupropion • Anticonvulsants: Carbamazepine, oxcarbazepine, lamotrigine, valproic acid, levetiracetam
Yes
No
Do you currently have, or have you previously had, a problem with misuse of or dependence on alcohol, illegal drugs, or prescription medication, or have you ever taken methadone? A urine drug test is mandatory on the first visit.
Yes
No
Are you currently pregnant or breastfeeding?
Yes
No or not applicable

If you are able to become pregnant or get someone pregnant: Are you or your partner planning a pregnancy, sperm/oocyte donation, or sperm/oocyte freezing during the trial or within 3 months after it ends, or would you be unwilling to use an acceptable form of birth control or remain sexually abstinent during that time?

(18) Select an option:
Yes
No
Are you generally willing and able to participate in a clinical trial for up to 20 months, regularly complete a patient diary, and attend doctor visits every 2 to 5 weeks? For example, this may not be possible if you expect to move far away or have trave
Yes
No

Have you used any THC-containing products (recreational or medicinal) in the past 7 days, or would you be unwilling to abstain from any THC-containing products (recreational or medicinal) during the trial? Examples: Marijuana, cannabis extract, THC gummies, or THC vaping products.

(20) Select an option:
Yes
No
Are you willing to take the cannabis-based trial medication for your pain and follow your state’s laws about driving while taking it?
Yes
No
Would you be able to avoid drug testing outside the trial during your participation (for example, testing at work)?
Yes
No
Have you participated in another interventional clinical trial involving a study drug or study device, or received a study drug or device, within the past 30 days?
Yes
No
Have you ever had an allergic or serious bad reaction to cannabis, sesame oil, or acetaminophen (Tylenol)?
Yes
No
Is driving or operating heavy machinery a main part of your job? This does not include your commute to and from work.
Yes
No

By providing your number, you confirm you are the subscriber or have authorization. View our Privacy Policy and Terms for details.

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